Sep 22, - Hemorrhoids cause pain, itching and discomfort that mimic a herpes infection. They are often felt as lumps or bumps around the anus. Because. Feb 18, - Anal herpes: Anal sex may spread the herpes viruses HSV-1 and HSV Symptoms include painful sores around the anus that come and go. Anal warts: Infection by the human papillomavirus (HPV) can lead to warts in and around the anus.